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  • What is Cellvizio?

What is Cellvizio?

Cellvizio is one of the two types of Confocal Laser Endomicroscopy

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Probe and Needle-based Confocal Laser Endomicroscopy
Compatible with any state-of-the-art endoscope and therapeutic procedures during endoscopy


Endoscope-based Confocal Laser Endomicroscopy
One endoscope dedicated to endomicroscopy

Cellvizio is a breakthrough technology

Cellvizio is an endomicroscopy system which generates optical biopsies, providing physicians with microscopic images of tissue instantaneously and in a minimally-invasive manner. This simple pattern recognition facilitates better decision-making and improved patient management. Clinical trials have shown that Cellvizio can provide benefits at each step of the patient management, and in multiple indications, including:

  • Barrett's Esophagus
  • Gastric Diseases
  • Bilio-pancreatic Strictures
  • Pancreatic Cysts
  • Inflammatory Bowel Diseases
  • Colorectal Lesions
  • Lung Nodules
  • Urinary Tract Lesions

A complete endomicroscopy platform

Cellvizio offers a choice of Confocal Miniprobes that were designed to answer the specific needs of each endoscopy field:

  • GastroFlex for Eso-Gastro-Duodenoscopy(EGD)
  • CholangioFlex for Confocal Cholangioscopy in ERCP
  • ColoFlex for Colonoscopy
  • AlveoFlex for Bronchoscopy and Alveoscopy

This makes Cellvizio a complete endomicroscopy platform that can benefit endoscopists from different fields who seek one common goal: to detect disease earlier and improve patient outcomes. 

Frequent and high-quality training opportunities 
Mauna Kea Technologies organizes frequent pCLE learning workshops at centers near you.

A strong community of users dedicated to the adoption of pCLE 
Mauna Kea Technologies is dedicated to accompanying the adopters of Cellvizio throughout their discovery of pCLE and their practice. From 2009 to 2015, a very strong community of luminaries met once a year at the International Conference of Cellvizio Users (ICCU), an event praised by GI leaders as an exceptional scientific and medical meeting. Now the International Society for Endomicroscopy (IS4E), established in 2016, gather the best experts in the field.

How does it work?

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Dr. Helga Bertani, Nuovo Ospedale Civile S. Agostino - Estense, Modena, Italy and Dr. Michel Kahaleh, Weill Cornell Medical College, New York, USA, performing a probe-based confocal laser endomicroscopy (pCLE) procedure with Cellvizio

The term 'Optical Biopsy' refers to methods that use the properties of light to enable the operator to make an instant diagnosis at endoscopy, previously possible only by using histological or cytological analysis. This (traditional) method of evaluation creates a significant delay in diagnosis, introduces the possibility of sampling error, and adds to the risk and cost of the procedure.

- Thomas D. Wang, MD, PhD Associate Professor, Gastroenterology
University of Michigan, USA