Cellvizio® vision is changing lives

Cellvizio, the world’s only real-time in vivo cellular imaging platform, is transforming gastroenterology. By enabling you to see precisely what’s occurring virtually anywhere in the GI tract, at the cellular level, in real time, Cellvizio reduces uncertainty and delay in the diagnosis and treatment of gastrointestinal diseases:1

Obtain instant relevant diagnostic information2,3

Make on-the-spot treatment decisions1

Evaluate response to treatment quickly and precisely4

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The Cellvizio® difference

Early, accurate diagnosis of gastrointestinal disease can be difficult with traditional endoscopic techniques, which offer limited diagnostic and therapeutic capabilities. The power of Cellvizio vision changes that.

Voir

Instead of blind biopsies, view the characteristics of cells in real time, inside the patient, with high-magnification video. Observe the mucosa for investigation of potentially cancerous tissue.

Comprendre

Classify high-grade dysplasia and early esophageal cancer with high accuracy.5 Characterize intestinal metaplasia and early gastric cancer.6 Differentiate responders from non-responders for ulcerative colitis patients.4

Agir

Perform better targeted biopsies,5 yielding on-the-spot characterization of abnormalities. Identify cancers,7 or rule out malignancies with more confidence,8 and avoid biopsies of insignificant lesions.9

Changer

Make earlier, more conclusive diagnoses.10 Perform fewer, less invasive interventions.11 Optimize treatment paths and patient care, for more favorable clinical12 and economic outcomes.9

GASTROENTEROLOGY INDICATIONS

BarrEtt’s Esophagus

Barrett’s Esophagus

Pancreatic cysts

Pancreatic cysts

Gastric disease

Gastric disease

Inflammatory bowel disease

Inflammatory bowel disease

Bilio-pancreatic strictures

Bilio-pancreatic strictures

Colorectal lesions

Colorectal lesions

tower

The Cellvizio® platform

The Cellvizio real-time in vivo cellular imaging platform uses Confocal Laser Endomicroscopy (CLE) advanced imaging technology to deliver cellular visualization virtually anywhere in the human body.

Learn more
  1. Wang K. et al. Use of probe-based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence. UEGW Journal, 2015.
  2. Ji R, et al. Confocal endomicroscopy for in vivo prediction of completeness after endoscopic mucosal resection. Surg Endosc. 2011;25:1933-1938.
  3. Jeon SR, et al. Optical biopsies by confocal endomicroscopy prevent additive endoscopic biopsies before endoscopic submucosal dissection in gastric epithelial neoplasias: a prospective, comparative study.Gastrointest Endosc. 2011;74:772-780.
  4. Hundorfean G. et al. Development and Validation of a Confocal Laser Endomicroscopy-Based Score for In Vivo Assessment of Mucosal Healing in Ulcerative Colitis Patients. Inflamm Dis. 2017.
  5. Sharma P. et al. Real-time increased detection of Neoplastic tissue in Barrett’s Esophagus with pCLE; Final results of a multi-center prospective international randomized controlled trial, Gastrointest Endosc. 2011.
  6. Li Zhen et al. Confocal laser endomicroscopy for in vivo detection of gastric intestinal metaplasia: a randomized controlled trial, Endoscopy, 2013.
  7. Shahid M.W. et al. Diagnostic Accuracy of probe based Confocal Laser Endomicroscopy in Detecting Residual Colorectal Neoplasia after EMR: A prospective Study. Gastrointest Endosc. 2012.
  8. Kiesslich R. et al. In vivo histology of Barrett’s Esophagus and Associated Neoplasia by CLE, Clinical Gastro and Hepatology, 2006.
  9. Al-Mansour. et al. SAGES TAVAC safety and efficacy analysis confocal laser endomicroscopy. Endosc. 2020.
  10. Napoléon B, et al. Confocal endomicroscopy for evaluation of pancreatic cystic lesions: a systematic review and international Delphi consensus report. Endosc Int Open. 2020.
  11. Le Pen C, et al. A health economic evaluation of needle-based Confocal Laser Endomicroscopy for the diagnosis of pancreatic cysts. Endosc Int Open. 2017.
  12. Palazzo et al. Impact of needle-based confocal laser endomicroscopy on the therapeutic management of single pancreatic cystic lesions, Surg Endosc. 2019.